I was diagnosed in 1996 with Hashimoto's. My TSH was 1210.66. My T4 was 0.5. I felt like crap. I was 30. I think the onset must have been very insidious, because I explained away many things for a long time. I had been on Prozac for a year for the accompanying depression. When I came off the Prozac, I had an increase in tingling in my hands and feet. That brought me to the doctor when I was finally diagnosed. In addition to extreme fatigue, feeling cold, having yellow skin, a puffy face, coarse hair, and a changed voice (I remember feeling like talking used a LOT of energy), I had memory prolems, depression, anxiety, paranoia. One reason I waited so long to tell a doctor something was wrong was I was afraid of being called a hypochondriac. Ahhh, the irony. Anyway, here I am 12 years later. I try to remember what it was like to feel so sick so I can appreciate feeling healthy. The really fortunate thing about hypothyroidism is how simple the treatment is. I actually felt more tired initially with the treatment--I think it's hard for the body to "speed back up." But, definitely, you will feel better.