On Lexapro - I couldn't orgasm EVER when I had sex with my husband. Since he's on Prozac and he doesn't orgasm either, he was to the point of "why have sex"? So I got off of it after five months and got on Wellbutrin XL. It took a while, but I finally did start having orgasms again. Now, just this past week, I had to resort to adding 5mg of Lexapro back with the 300MG WB because I was so irritable and nervous, I couldn't stand it any more. Had sex Sunday night - and no orgasm, very very frustrating. Felt like I was on the very edge of it - just coluldn't quite get there. I hope this is a passing thing!!