My daughter is on 300 mgs of Lithium a day, along with 10 mgs of Prozac. This combo seems to be working. I guess everyone is really different. She's only been on it for 2 months, but I've noticed a tremendous improvement in her moods. She's still really messy, but hey, she's only living with us for a few more weeks. Should she be having her blood levels monitored?? She'd never do that on her own!!