I had my first Reclast infusion yesterday, now 23 hours ago. It took 30 minutes, during which I felt absolutely nothing. Several hours later I began to feel very faintly achey as if maybe I were getting a cold, and that is all I have felt since. After a night's sleep I still feel a little achey but not enough that I would even take anything for it. I have no joint or bone pain, no fever, no headache, none of the other side effect symptoms listed online. My appetite is normal. This morning I am going out to do some errands as later it's supposed to snow. I chose Reclast because I had heard such horror stories of esophageal and stomach problems from Fosamax, which I have been refusing for years. BTW my Blue Cross paid 80% of the $1250 cost; my share was $250. On a yearly basis that pro-rates to less than $21 a month since the treatment is given once a year for three years. I am aware of possible long-term side effects (ONJ, atrial fibrillation) but as I am at the 99th %ile of fracture risk, I put my need for independent function ahead of everything else. If it came to that, I could still get to the grocery store with a pacemaker, but not with a broken back, and I could get A-fib even if I didn't take Reclast. I feel I have made an informed decision. I'm also on calcium and a lot of Vitamin D. My doctor is an osteoporosis specialist. To me this is like flying on a plane: you pick a reliable airline, buy your ticket, and go, and at some point the adventure becomes about trust. God help us all.