I am on both Remeron (Mirtazapine - antidepressant) and Klonopin (for anxiety) and neither of these meds have had a negative effect on my Libido. I think Klonopin has increased it actually..I then went on the website and it said one of the side effects of Klonopin is that it can increase Libido. There are several antidepressants that do not affect libido...unfortunately, this can be a side effect of SSRI's. You didn't mention what antidepressant you are on now, but I know that Prozac is an SSRI. Can you talk to your Doctor about Wellbutrin (that has a very low side effect of decreased libido), Remeron or a tricyclic antidepressant?