Discussions that mention seroquel

Sleep Disorders board


anyone taking seroquel for sleep? my dr. prescribed seroquel for sleep but after researching it i am scared to take it. it is an antipsychoticdrug used mainly for schizophrenia and bi-polar disorders. i am a diabetic and its side effects say it can cause diabetes and raise blood sugar levels and cause severe constipation and weight gain. would you want to take this? and does anyone?
p
Quote from pleasantville:
anyone taking seroquel for sleep? my dr. prescribed seroquel for sleep but after researching it i am scared to take it. it is an antipsychoticdrug used mainly for schizophrenia and bi-polar disorders. i am a diabetic and its side effects say it can cause diabetes and raise blood sugar levels and cause severe constipation and weight gain. would you want to take this? and does anyone?
p
i did try it and 25mgs did nothing. i was wide awake 2 hrs. later. then tried 50mgs and slept for 4 hrs. i can see that i would need a higher dose of seroquel and that is what i am afraid of. i am already dependent on 3 mgs of ativan daily. thanks for replying. also, did your dr. have any qualms about prescribing it to a diabetic? any constipation problems?

p
My Doc just put me on Seroquel. Once I read about the side effects I was concerned as well. I also take Trileptal, Xanex, Klonipen.........All at night. Plus I have a CPAP machine to help me breath. I don't have Apnea, but I have always been a shallow breather. Diabetes and all the other symptoms run in my family. I don't want this medicine to make it worse. I am on a 50mg dose and don't really notice any side effects accept that I sleep like a log. I'm hoping this medicine will work for a short term solution until something better can be worked out for me.
My husband has OCD (and apnea, too), but his psychiatrist prescribed Seroquel for him to help him sleep. It was a nightmare (no pun intended). His anxiety increased exponentially, and he thought he was going to lose his mind. He was breaking down and crying at work, and flaring into fury at our son. He told me he began to think we'd be better off without him. We realized that he felt much worse if he took the pills on even 2 consecutive nights. What angered us the most is that the psychiatrist never warned us of any side effects. On a particularly bad night, my husband called the pharmacist at our local hospital and asked if it could really be the Seroquel. He replied that a full 25% of patients go through just what my husband did. He told my husband it would be a rough ride, but to just try to get through the 24 hours it would take for the medication to get through his system. Later I read the testing process this drug went through, and the patients who suffered, and it made me angry all over again.
Well I might be the only one here with a good Seroquel experience, but I just thought I'd post anyway. I started taking Seroquel about 2 years ago, combined with several other drugs for depression. The Seroquel was only for sleep, and I took 400 mg. I would sleep like a log (first time in years) but it was hard to get up in the am- the sleep was so peaceful it felt like I became addicted to it. Over time I weaned off my other depression drugs, leaving only the Seroquel for sleep. I have slowly weaned off that as well, and am only on 50mg a night. There have been recent studies that show Seroquel is the only known drug that can reduce suicidal ideations, and is now used to treat acute episodes of suicidiality, both to prevent an attempt, and if not used prior, to help the person after an attempt. It also has been shown to reduce negative thoughts and increase optimism. While I didn't start taking Seroquel for that purpose (since 2 years ago they didn't know this) it actually explains my experiences well. I didn't realize it was due to the Seroquel (hey, maybe it's not and I've just gotten better, I don't know) but I have gone from being suicidal nearly every day for a year, to being happy, healthy, etc. I can deal with life, I can deal with problems, and I don't sweat the small stuff. I've tried over 30 different drugs, and was labeled drug resistant by every doc I've seen. However this was THE one. I'm a true believer that this is only my experience, I've had horrible experiences with some drugs that other people thought were life savers. It just depends on what it does for you. For me, I thank God for Seroquel. It's taken away the biggest stress in my life, which was knowing that at the end of the day, I would just lay for hours. Now I know I take it, wait about 2 hours, and fall into a peaceful (albeit vivid) sleep. I hope this helps, and I hope you find something that works for you.
Quote from pleasantville:
i did try it and 25mgs did nothing. i was wide awake 2 hrs. later. then tried 50mgs and slept for 4 hrs. i can see that i would need a higher dose of seroquel and that is what i am afraid of. i am already dependent on 3 mgs of ativan daily. thanks for replying. also, did your dr. have any qualms about prescribing it to a diabetic? any constipation problems?

p


I wouldn't take it, it's a major tranquilizer and quite bad for the nervous system.

THree mgs. Ativan and still have sleep trouble? That might be the key. Ativan and other benzos(or benzo like sleep meds) are great for sleep but over time they actually can worsen pre-existing insomnia conditions. THe GABA receptors are downregulated as the brain tries to adapt over time, causing tolerance and dependancy.

Downregualtion means less GABA, less of the calming/sleep chemical receptors and also as a defense mechanism, the brain also upregulates opposing receptors to the drug (excitatory receptors).

So basically, you are eventually left with too many excitatory receptors and not enough inhibitory ones which makes sleep even more hard to get than before! Also, a new range of excitatory chemicals might lead to anxiety and nervousness.

So next move is, since they don't like to exceed prescribing limits on benzos, the docs get out the big guns...the major tranqs, which may work some but they aren't really able to cover the receptors the benzos do.

What's the answer? For me, it was tapering off my Ativan and putting up with a somewhat lengthy withdrawal. Looking back, it was sure hellish for awhile, but now I feel so much better and my slight lingering sleep issues are nothing compared to the problems I had while on the meds....for example, taking 2 mg. Ativan at bedtime everynight and not sleeping at all for several nights in a row plus anxiety/panic attack withdrawals during the day!!!

I basically now sleep good, without as much as a Tylenol PM or chammomile tea. Not as good pre-benzo, but still noticing improvements even a few years off which is amazing to me, so continued recovery has no time limit. And, I get more sleep now than when I was on that stuff so I've already won the battle.

Look up the free online Ashton Manual on benzos. Seems alot of people end up with trouble with them, which can lead to not only more meds like antipsychotics and antidepressants (just to get a night of sleep or calm down) but also to various mental and physical conditions.

I decided not to go down that road and am so glad I didn't but that decision is up to each person. But everyone I know who is still on some med, sleep is a constant problem for them which is sad because I've been there, I know how torturous it is and I know the answer. But I will admit it was very hard and took alot of patience.

Never CT a benzo as seizures are a possiblilty.