Discussions that mention simvastatin

High & Low Blood Pressure board

It seems the frequency of eating grapefruit is key too. A case study in Neurology (2004, vol. 62(4)) reported on a woman, who went from healthy and exercising regularly, to true rhabdomyolysis in just 2 weeks (only aggressive treatment by the hospital avoided renal failure). She was on zocor, and had started, 2 weeks prior to the crisis, to eat a daily whole grapefruit with breakfast. So, the effects of frequent consumption seem to be cumulative.

Also, the particular statin seems significant. Zocor (simvastatin) seems to be affected by grapefruit more then others (at least according to the UK's Medical products department, or whatever "MHRA" stands for).