Five weeks ago I had a Synthroid dosage increase from 75mcg to 100mcg. I felt terrible to begin with but after three weeks I began feeling better and at four weeks I felt pretty good. However, in the past 3 or 4 days I have had anxiety, some tiredness, and some brain fog return. I called my endo and they told me to take a 75mcg one day and a 100mcg Synthroid the next. Is it possible that the 100mcg is a little too much for me? Secondly, does this alternate dosage seem like a proper protocol or should they have just prescribed 88mcg? Thanks for your comments.