Discussions that mention synthroid

Thyroid Disorders board


My History:
I have had my levels all over the place for a while now. About 3 months ago I started seeing a new Endo and he adjusted my Synthroid dose from .220mg to .175mg (8 weeks now) - he said I was overmedicated. I am feeling better than I did 3 months ago, but I still feel terrible. I can't gain any weight, I am anxious all the time, my heart feels like it is gonna pop out of my chest at times, my stomach is still kinda messed up, and now I am starting to feel a tickle or like food is stuck in my throat.

I had my Thyroid removed 4 years ago due to cancer.

My lab results are:

TSH 0.834 (0.35-5.5)
Thyroxine (T4) 9.5 (4.5-12.0)
T3 Uptake 40 (24-39)
Free Thyroxine (t4) 3.8 (1.2-4.9)
Triiodothyronine (t3) 143 (85-205)

Any feedback would be greatly appreciated!!!!

It simply looks as though you are taking too much. My tsh has never been under 5! I am fighting with my doctor to try to get mine to 3. You were over medicated and still are. However, Synthroid has a long half-life and the higher dose that you were taking will stay with you for some time. I don't think 3 months though? Talk to your doctor about lowering your dose and raising your tsh to about 2 or 3.
Looking at your labs, I think your T4 is OK, but your body apparently doesn't. The high T3 Uptake score indicates that your body is producing binding proteins to hold some of the T4 because it feels you have a little much. This is often seen in hyperthyroid cases.

Now, on the other hand, your T3 is about middle of the road. Since it is lower in range than your T4, one of two things is going on: (1) your body is slowing conversion of T4 to T3 because it thinks you are hyper, or (2) more likely, you are just not converting T4 to T3 well to begin with.

What can you do about it? Here are some options in no particular order:

(1) Ask your doc to lower your dose of Synthroid to 150 or a little lower and add in 10mcg Cytomel split into two 5mcg doses a day. Many doctors are reluctant to try this and think it is risky. Clinical trials have shown otherwise, though. This would lower yout T4 a little and raise your T3 and would probably drop your TSH a little, which is better in light of your history of thyroid cancer. Advantage: Easier adjustment of T3 and T4 levels than other combination options.

(2) Ask your doctor to change you to a combination T4/T3 med such as Armour Thyroid, which is my preference. The same things as above apply, except that many doctors think Armour is unstable, dangerous, and antiquated. They are wrong. It has proven to be CONSISTENTLY more stable than Synthroid (or any other synthetic med, for that matter) over the last several years. Good luck with this approach. Advantage: Cheaper thna Synthroid and MUCH cheaper than Synthroid and Cytomel combined. Natural meds may contain other nutrients and hormones that might be beneficial though they haven't been studied.

Leave your doctor out of the loop and start taking some Selenium on a daily basis. This might be a good idea, even if your doc goes for one of the other options. Start at 200mcg a day for at least a month, and then drop to 100mcg a day for maintenance. This will help your body convert T4 (Synthroid) to T3. It will lower your T4 just a little, since some of that T4 is being converted to T3. It will raise your T3, since you'll be better able to convert, and since T3 is more active than T4, you may drop your TSH some, again, better in light of your history of thyroid cancer. Advantage: Inexpensive and can be bought at any health food store or pharmacy that sells vitamins and minerals, and at many grocers. Lets your body decide how much T3 it needs and convert as needed.

Any of these methods will probably work and will make you feel better and help with moods, as well.