Hi everyone. I am new to being hypo and also to this board. I was just diagnosed last week but have been having symptoms for three or four years now. My thyroid is also just slightly enlarged. Anyway, I have always reacted VERY strongly to all meds. I was put on antidepressants over a year ago and the dr kept having to try me on something new because of the severe side effects I'd have and that was with always being on the lowest dosage possible. I always have to take pediatric doses and then sometimes it's too much.(I'm off those now) I was just put on 25mcg of Synthroid (what is that in mg by the way?) and I am already starting to feel some effects- all good- except I started to feel jumpy ( a problem I have had with many other meds) So this morning I broke the pill in half and took one in the morning and one in the afternoon and that seems to be better. Taking it all at once, my heart beat harder than usual and I felt very panicky and shaky. Has anyone else had this problem? I know this is a very small dosage of synthroid, but like I said, I have this problem with meds for some reason. I am supposed to start doubling it in a few days and I don't think I will be able to at this rate! By the way, my TSH was 6.7. Thanks!!