I just have a few questions. First off, I have been on Synthroid many years and am currently on 0.1 MG per day. I just had my TSH checked for my yearly exam and it was 5.53 which is just above the high normal range of 5.5 according to the Dr. I have apt. 3/17 to go over with her. I have been terribly tired for the last 5 mos. or so, hard to get up in the morning, irritable, etc. so now that I found out the level of my TSH has gone up, I am fairly certain I need my dose "upped". In her letter she suggested testing in 3 mos. to see if it needs to be changed, I am thinking it needs changing now. About a year ago I had to switch Dr.'s due to insurance and this Dr. isn't the most knowledgeable about the whole thyroid thing. (although I don't know much either other than what I learn here on the net). My old Dr. always kept me around 2. She felt lower on the range was better as long as I felt OK. This Dr. feels if it's in the normal range, anywhere in it...it's fine. I was having symptoms last year at this time and my TSH was between 4 & 5 (can't remember exact) and she assured me that my symptoms must be something other than the thyroid level because it was in the normal range. I ended up staying on the 0.1 MG because she said it couldn't be my thyroid and I couldn't convince her otherwise. I am hoping for some info and maybe some advice on Dr.s & how to handle this with her. I am at the mercy of a PPO and can only go to one place where my insurance will pay full amount. I could switch Dr.s within the clinic, but I prefer female to male and there's not a lot of choice in that area. Plus I could end up with another just like her too...who feels if it's in range, it's fine. Can I as a patient insist they increase the dose to keep me at a certain TSH if I find that I feel better? If they don't test T3/T4 and all that, is this TSH test a good enough indicator or should I insist on different or additional tests? Also...can anyone tell me what a high dose of Synthroid would be? In other words...how high of a dose can a person go? I'm on 0.1 MG right now...is this very low, moderate, high? And does anyone know what happens if the dose keeps having to be increased? Does this mean eventually the thyroid will quit altogether and the whole thing will need to be controlled by the thyroid medication? I'm assuming they don't remove a thyroid unless it causes a problem, so if it just stops I suppose they just increase dose. I have a feeling I'm low on the dosage scale, just wondering though. Thanks for any help.