Thank for the info. I was told and i was thinking that it would take a while for my body to adjust to the changes. About my heart when i first went into the doc it looked like i had chf. On the xray my heart was around twice the normal size. My paluse was in the 50's and under strain "working out" it would only reach the 60's. So i had a echo done on the heart. It was done about 4-6 weeks after going on synthroid. They said everything looked great as far as heart function ect. ect. And it was only slightly enlarged at that point. It seems as everything is ok now.