When I was Hyper for several years (though didn't know it), my acne was terrible, tried everything under the sun - antibiotics helped for a while. I also had the large cysts and the acne was worse than when I was a teenager. Anyway, before I decided to go with RAI treatment I was put on Tapazole, and for two months my skin cleared up and it looked great! Well I have since had RAI treatment (it's been almost 3 months now),the acne got worse but is starting to clear up now as my thyroid levels have started to change - I am taking synthroid 100 mcgs. I am convinced my acne caused by my thyroid. You will not read much about your thyroid being acne related, but a few sights will say it causes acne.