Discussions that mention tamoxifen

Cancer: Breast board

I am 46 years old and am at high risk for breast cancer so my doctor wants me to consider taking Tamoxifen as a preventive measure. I've been reading about it and see that it is only effective in treating estrogen receptor-positive breast cancer and not estrogen receptor-negative cancer. Is one more prevalent than the other? Does anyone have any advice for someone in my position? It seems like the benefits outweigh the risks, but I'm still just not sure what to do. I'd appreciate any advice!

Thank you!

I must say I never heard of anyone taking this medication without having cancer. You always learn. I know lots of people have to take tamoxifen after a breast cancer operation to prevent cancer to recur.

I had a lumpectomy, followed by chemo therapy and radiation therapy. My oncologist told me I could not take tamoxifen because I am estrogen receptor negative and therefore the medication would not do any good for me.
Hi Tinamarie,
I too, am at high risk for breast cancer and after consulting my gyn went on Tamoxifen for 5 years. We both felt that the benefits of taking the medication far outweighed the risks. I've been off it now for 3 years. I did have the "hot flashes, weight gain", etc. sometimes associated with taking it. But it wasn't so bad. At least, I feel that I've done everything short of surgery to prevent breast cancer. Hope this helps.