Discussions that mention timolol

High & Low Blood Pressure board


Sandy,
Almost EVERYBODY has a slow time getting off beta-blockers. The proper approach with Toprol is to go from 100mg. to 50 to 25 and then even to 12.5 mg. if you are good with a pill splitter.
Since they work by blocking receptors to adrenaline and noradrenaline, our bodies make more of these catecholemines to compensate. If we suddenly remove the blockade we are overwhelmed by a flood of these "stress hormones." Tachycardia, hypertension, anxiety, panic, and even angina, are the frequent results.
Take 25 mg. for a couple weeks and then move down to 12.5.

I woudn't use an alpha blocker (like terazosin) unless I had prostate enlargement: my MAIN reason:
[QUOTE]use of alpha blockers has been found to increase the risk of heart failure over long–term use.

The link between heart failure risk and alpha blocker use was found during the landmark ALLHAT study (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial). ALLHAT also determined that other medications were preferred for treating for high blood pressure because they also lowered the risk of heart attack, stroke and other heart diseases.
That's a BIGGIE especially considereing we take these drugs to help PREVENT heart disease.

From a British medical site:
[QUOTE]Antihypertensives . .
ACE inhibitors (eg enalapril, lisinopril) .......Impotence
Alpha blockers (eg prazosin, doxazosin) ...... Impotence
Beta blockers (eg atenolol, propranolol and including timolol eye drops) ....Impotence
Calcium channel blockers (eg verapamil, nifedipine) ...... Impotence
Clonidine ...... Impotence, Decreased sex drive, Delayed or failure of ejaculation
Methyldopa ......Impotence, Decreased sex drive, Ejaculatory failure
Thiazide diuretics (eg bendrofluazide) .... Decreased sex drive, Impotence, Ejaculatory disturbances

Distressing isn't it?