Discussions that mention toprol

High & Low Blood Pressure board


I've been on Metoprolol for 6 months now. I am on 25 mg xl, once a day. My side effects keep changing. For the last 2 wks or so, I had insomnia, and now, for the past couple of days or so I can sleep. Also, I get hot flashes on and off. Once in a while, blood pressure spikes, or increased blood pressure, higher pulse, especially in the mornings. Sometimes I have more energy, other days not. Sometimes palps, other times not. Also, last wk for a few days, I was incredibly irritable, and now I'm ok.
Could this be an adjustment that needs to be made to my dosage, or is this just normal ?
I can say that their have been numerous side effects posted on the web recently abou METOPROLOL side effects. It appears that CONSUMERLABS and PEOPLES pharmacies have tested the Generic TOPROL-XL called METOPROLOL XL, and found the the pills to be inferior and not equivalent. You have to ask for the brand name "TOPROL XL" by Astra Zeneca. I'm not sure about atenolol, but the brand drug Atenolol is called TENORMIN, and a prescription for 90 days is well over $100. The generic Atenolol is about $3.00 at Walgreens. Is there a difference, you decide. I have not had any problems with TOPROL XL brand. Sleep problems could arise from the ingredients, and the inferior release properties of the drug...

P.S. This is just my opinion from what I've read....
My point about the generic difference is that for certain brand name drugs, the generic "Equivalent" has not been proven to be equivalent. Especially for TOPROL XL, the only generic which was tested and proven to be equivalent is manufactured by PAR pharmaceuticals. All others are junk, according to PeoplesPharmacy and CONSUMERLABS. Sometimes a good pill takes a bad rap. I believe it's worth giving the brand name drug a try if side effects and tolerabilty remain horrible, especially for cardio-meds. If a pill is not manufactured to specific requirements, the drug can either release it's ingredients too soon or not soon enough. This can lead to skin flushing, irregular heartbeats, sudden dizziness, body aches etc... Also, beta blockers are all different in regard to side effects. ATENOLOL side effects are different than COREG or TOPROL side effects. Most importantly, not everyone experiences the same side effects with the same drug or class of drugs. The newest beta-blocker released is called "BYSTOLIC". This pill was designed to eliminate many of the side effects of the older beta blockers. Many on this board and others have given it high praises....