Hi everyone, I am new to the site and am searching for any and all information I can find since my doctor doesn't seem to answer any of my questions or at least it seem as though I am just another case. I have been diagnosed with RA and I am currently on Trexall 10mg. I have only been on it for one month, but previously in 2001, I was on it for 2 months and at that time I went through some serious depression,(never before relating it to RA) but now I started the medicine again and here it comes, depression again! Has anyone else had any similar situations? I'm scared of medicines as it is, so any info would be much appreciated.