Discussions that mention tylenol

Restless Leg Syndrome board

Yea, Flexeral is a bad one for aggravating RLS or causing a flareup. There are a lot of drugs that can make RLS worse. Some anti-depressants, antihistamines, Benadryl, and Tylenol PM just to name a few.
I am anemic. My ferritin level was only mildly low but caused severe RLS. I manage it by taking an iron supplement when I feel it coming on (which thankfully is not very often anymore). It took about 4 months to bring my iron level up to normal, and now I only take it as needed. The iron works in less than an hour now. Usually only 30 minutes or so. You may want to ask your doctor for a complete CBC if it hasn't been done already. Some people have gotten relief from Mirapex, a drug for Parkinson's disease, Folic Acid, B12, or Magnesium. Some people get relief from taking a very hot bath. Some even swear by putting a bar of soap under the sheets near their legs. There are just too many medical treatments and home remedies to list. Your doctor can probably tell you which treatment will work best for you. You can have relief, and you can get sleep.