Discussions that mention vicodin

Pain Management board


[QUOTE=123dietdrpepper;3357331]What does it mean when they say a medication is a morphine like opiod agonist? Does it contain morphine? If someone is allergic to morphine can they take this medication?

Morphine-like just means it's a narcotic, either natural, semi synthetic, or totally synthetic. Morphine and codeine are pure natural narcotics and are referred to as opiates, derived directly from the opium poppy. Oxycodone is a semisynthetic narcotic and is referred to as an opioid. A fully synthetic narcotic (opioid) is fentanyl, and methadone is also fully synthetic.

An agonist is one that is attracted to and fills an opioid receptor (usually the µu receptor) for analgesia (pain relief), sedation, and the other side effects of pure agonists. Morphine is a pure agonist, along with similar opioids like oxycodone, hydromorphone (dilaudid), oxymorphone (Opana), hydrocodone (Vicodin), methadone, fentanyl (Duragesic patch, Actiq, Fentora), etc. Buprenorphine and Stadol are partial agonists and can cause withdrawal in someone dependent on pure agonists. These can also be called partial agonist/antagonists depending on other compounds that might be present. Naloxone is a pure antagonist, also derived from the opium poppy, and it will for sure send a person dependent on pure agonists into withdrawal. This is used when someone has overdosed on a pure agonist, and when administered will immediately kick the agonist out of the opioid receptor and take its place, making for a very bad trip for the addict.

Allergy - some say they are allergic because they experienced a side effect and it bothered them so much they decided to switch. This isn't really an allergy. An allergy will produce hives, trouble breathing, throat swelling up, tightness in the chest, etc. It's also refered to as anaphylactic shock. One who has suffered anaphylactic shock will have to be very careful with any other opioid and the doc can help with this. If someone has just had difficulty with a side effect of one particular narcotic then they can probably find relief with another one of the many available. Sensitivity to morphine probably means that person will also have trouble with codeine, and should try oxycodone or hydrocodone or oxymorphone. There's always Tramadol (Ultram) as well.

steve