I started taking Wellbutrin XL about 6 weeks ago. I did not notice anything different about my labido or ability to orgasm. After 3 weeks I added Lexapro and it took me longer to have one but I still could. Then I had an allergic reaction to Lexapro and now have switched to Zoloft and so far it takes me a little longer but less then what the Lexapro did to me. Basically my verdict is Wellbutrin XL had no sexual side effects for me at all. I am taking 150mg a day.