Abilify can be used as a mood stabilizer, it's really being touted as a drug for bipolar disoirder, but proabably has uses in depression also as it works similarly in the brain, I would suppose. My daughter has been on it for about a month and says it seems better than Zoloft, Celexa, Lamictal, Welbutrin or Paxil. Trying to treat depression is really a crapshoot. What works for one won't necessarily work for another. My daughter's side effects were a sense os buzzing ine her hands and feet but it was nominal and not bothersome at all. Some appetite changes but I don't think anything serious. Good Luck, hope it helps.