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Re: osteopenia in young women

Re: osteopenia in young women

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Posted by Laurie C. on August 26, 2000 at 14:54:50:

In Reply to: osteopenia in young women posted by a brumblay on June 21, 2000 at 23:00:08:

: My 21 yr old athlete daughter was diagnosed with osteopenia of the spine. Her GYN prescribed Actonel plus calcium supplements. After doing internet research I concluded that it was unwise for my child to take this drug at such a young age! (possibility of birth defects in the future) Does anyone know anything about this topiC? I would appreciate some comments!

Dear Brumblay,

I am sorry your daughter must endure this at such a young age. I am told I have osteopenia and; although not in my 20's, I am still of childbearing age. I'm engaged and hope to get pregnant so I do have comments on this topic especially since my doctor gave me actonel. I read the PDR very carefully. No studies; of course, on pregnancy in humans on this drug has been done. The animal studies show that ther is incomplete ossification of the skull and sternebrae in the fetus' of rats treated at a dose of actonel which is 5 and 27 times the dose prescribed for humans. However; in rats given a dose which whould be equivalent to a normal human dose, periparturient hpocalcemia and mortality of the pregnant females allowed to deliver was noted. Obviously, if you want to get pregnant you must go off the drug. From this little bit of data it seems (note I say seems) fairly safe to assume a low likelihood of fetal abnormalities at the normal human dose. (How far can you deduce from rats to humans?) Same type of stats with fosamax. Ask your doctor about calcitonin. Have you also considered alternative methods? Some evidence that horsetail may be a helpful herbal treatment. (Helpful and effective are two vastly different things, I know)

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