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Re: Dr. W. - Lamictal

Re: Dr. W. - Lamictal

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Posted by MLWhitworth, MD on March 29, 2000 at 06:36:06:

In Reply to: Dr. W. - Lamictal posted by Skye on March 28, 2000 at 23:07:17:

I haven't prescribed the drug but am somewhat familiar with it. It is chemically unrelated to the other anticonvulsants but seems to act on sodium channels. Generally I do not give up on Neurontin until 3600mg per day is reached. As for central pain, sometimes deep brain electrostim is used...check out the medtronics web site. Thalamic lesioning is not often done anymore. I know of no good methods of treating central pain...there is no single entity that works for even a minority of patients. I will keep looking though and post here if I come upon anything.

: Dr. Whitworth, you've helped me before and I appreciate it. I have SEVERE thalamic pain since excision of T8-10 ependymoma in Dec. '97. I also have syringomyelia C7-T11. Nothing has helped-including spinal cord stim (electrode is glued to my brain stem.) I recently tried 3 day intrathecal infusion of fentanyl/bupivicaine-a high dose-and it didn't touch the pain. My pain is bilateral hips, legs and feet and I'm told DBS is out of the question. I'm in agony and only 46 yrs old. The only thing that helps is my pm dose of Elavil and Klonopin that mercifully knock me out for the night. My question is this:I read in the ACPA booklet about a new drug, Lamictal, an anticonvulsant that is used for central pain. Neurontin certainly hasn't helped me. In your experience, have you tried Lamictal? And are thalamotomies archaic? I read literature that basically said "they" aren't sure central pain necessarily originates in the thalamus. Too deep for me to go into now-I'm in so much pain. Thanks for reading.

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