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Posted by MATT JANSKY on November 04, 2000 at 18:24:15:

In Reply to: Re: A cure for Parkinson's disease? posted by Betty D. on October 28, 2000 at 17:22:52:

: : This is the most significant progress I have read as of today. Dr. Lieberman posted this article which was published in "Science". Their was a list of what I assume to be the research sites for the study and they are Chicago, Switzerland, Wisconson and France. In "plain English", a factor called GDNF is delivered to the appropriate site attached to a virus. They found the GDNF reversed the process of the dopamine producing neuron's destruction and also induced regeneration of the neurons in primate models of Parkinson's disease. Thw title of the message is "Article from Science of importance to Parkinson's disease patients." Now we have to hold our breath and hope the GDNF factor will work the same way in human subjects and not have any serious side effects. I am impressed! Bruce
: :: Bruce, This seems to be the same article that was in our daily paper. "Relief for Parkinson's Disease"?....Washington: A gene therapy experiment relieved severe symptoms of Parkinson's disease in monkeys and experts say the technique offers promise for treating the 1.2 million Americans who suffer from the disease, experts say. A virus that had been joined with a gene that prompts production of dopamine, a chemical neurotransmitter, was injected into the brains of monkeys who had chemically induced Parkinson's disease. These monkeys that had severe symptoms of Parkinson's were restored to near normal by the gene therapy, said Jeffrey H. Kordower, first author of a study appearing today in the journal Science. Friends, this is another promising avenue for finding THE CURE!!!!!
: Betty D.
Thanks, folks-- very helpful and encouraging info. If you have any other information-- links to relevant URLs, updates, or information about trials-- please post or even e-mail me directly, if that's not too presumptuos... my first time on this message board, and I'm quite impressed, will check in again, thanks again -- Matt J

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