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Re: How does Naprosyn effect a pregnancy?

Re: How does Naprosyn effect a pregnancy?

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Posted by Munchkin on December 13, 2000 at 01:54:50:

In Reply to: How does Naprosyn effect a pregnancy? posted by Barbara on December 06, 2000 at 15:22:09:

I found this at one of my web sites I use for my work doing medical transcription.

Pregnancy Category B

Teratogenic Effects: Reproduction studies have been performed in rats, rabbits, and mice at doses up to 6 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to the drug. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, the drug should not be used during pregnancy unless clearly needed. Because of the known effect of drugs of this class on the human fetal cardiovascular system (closure of ductus arteriosus), use during late pregnancy should be avoided.

Non-Teratogenic Effects: As with other drugs known to inhibit prostaglandin synthesis, an increased incidence of dystocia and delayed parturition occurred in rats.

Nursing Mothers

The naproxen anion has been found in the milk of lactating women at a concentration of approximately 1% of that found in the plasma. Because of the possible adverse effects of prostaglandin-inhibiting drugs on neonates, use in nursing mothers should be avoided.

As for side effects in general for yourself, this is considered a nonsteroidal anti-inflammatory agent, similar to Advil, Motrin, Aleve... common side effects are GI upset, GI bleeding, and ulcer development. I listed the URL for the site so you can read about all the side effects. Even if one person has an adverse reaction, they have to report what that symptom was, so don't let all the problems worry you. The biggest problem seems to be GI upset with it.

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